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NAME
Amprenavir |
BRAND
Agenerase |
CLASS
HIV protease inhibitor (PI) |
COST
$7,994/yr., $666/month |
STANDARD DOSE
Eight 150 mg (1200 mg) soft gelatin capsules twice a day, no food restrictions. Take a missed dose as soon as possible, but do not double the next dose. Approved for children ages 4 and older. Grape bubblegum, peppermint flavored liquid. Adults should not use liquid if possible. |
POTENTIAL SIDE EFFECTS
Nausea, vomiting, abdominal pain, taste disorders, fatigue, headache, rash anemia, colitis, bruising easily, prolonged bleeding, depressive mood disorders, circumpolar parenthesis (tingling or numbing around the mouth) and peripheral parenthesis. Gaseous symptoms are common and may be severe. Taking with food may help, but check for pancreatic when there is severe stomach pain. Seen with all the other protease inhibitors are high blood levels of cholesterol and trigecerides. (fats) and perhaps associated heart diseases, lipodystrophy (body fat changes, including thinning of the face, arms and legs, with or without fat accumulation in the stomach, breasts, and sometimes upper back) worsening or new cases of diabetes, symptoms include increased thirst and hunger, frequent urination, unexplained weigh loss, fatigue and dry itchy skin, see your doctor promptly and increased bleeding in hemophiliacs. |
POTENTIAL DRUG INTERACTIONS
Do not use Zocor or Mevacor lipid-lowering drugs; suggested alternatives are Liptiro, Lescol, Baycol and Pravachol (looks best on paper for protease inhibitors) Hismanal, Orap, quindine, Rythmol,Seldane, Tambocor, Vascor, and Versed. Protease inhibitors increase blood levels of Viagra (sidenafil citrate_ and Viagra dose should be started at 12.5 mg increased as needed and tolerated. One report suggested Viagra should start at half that when taken by someone on Norvir. It's recommended that people do not exceed 25 mg in a 48-hour period because of potential for fatal reaction. |
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